BDBM435049 (2S)-1-(benzofuran-2-ylsulfonyl)-N-[[3-isopropyl- 2,4-dioxo-1-[6-(trifluoromethyl)-3- pyridyl]pyrimidin-5-yl]methyl]pyrrolidine-2- carboxamide::US10584116, Example 29

SMILES CC(C)N1C(=O)C(C=C(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)C1=O)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=YTXJELCYXHBTEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435049   

LigandPNGBDBM435049(US10584116, Example 29 | (2S)-1-(benzofuran-2-ylsu...)
Affinity DataIC50: 30nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent