BDBM435050 (2S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-N- [[3-isopropyl-2,4-dioxo-1-[6-(trifluoromethyl)- 3-pyridyl]pyrimidin-5-yl]methyl]pyrrolidine-2-carboxamide::US10584116, Example 30

SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(nc2)C(F)(F)F)c1=O

InChI Key InChIKey=KUPHFKFESJUDAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435050   

LigandPNGBDBM435050(US10584116, Example 30 | (2S)-1-(5-fluorobenzofura...)
Affinity DataIC50: 10nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent