BDBM435056 (2S)-1-fro[3,2-c]pyridin-2-ylsulfonyl-N-[[3- isopropyl-2,4-dioxo-1-[5-(trifluoromethyl)-2- pyridyl]pyrimidin-5-yl]methyl]pyrrolidine-2- carboxamide::US10584116, Example 36

SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3cnccc3o2)cn(-c2ccc(cn2)C(F)(F)F)c1=O

InChI Key InChIKey=XIPWBPDWHQJWKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435056   

LigandPNGBDBM435056(US10584116, Example 36 | (2S)-1-fro[3,2-c]pyridin-...)
Affinity DataIC50: 200nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent