BDBM435067 (2S,3S)-1-(5-fluorobenzofuran-2-yl)sulfonyl- 3-hydroxy-N-[[1-isopropyl-6-oxo-5-[4- (trifluoromethyl)phenyl]-3- pyridyl]methyl]pyrrolidine-2-carboxamide::US10584116, Example 47

SMILES CC(C)n1cc(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cc(-c2ccc(cc2)C(F)(F)F)c1=O

InChI Key InChIKey=FXNIYZIWBXBVOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435067   

LigandPNGBDBM435067(US10584116, Example 47 | (2S,3S)-1-(5-fluorobenzof...)
Affinity DataIC50: 230nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent