BDBM435145 US10584127, Compound E1-9.2::US11136328, Compound E1-9.2::US11752155, Compound E1-9.2B'

SMILES Cc1ccc(COC(=O)N2CC[C@H](CNc3nc4ccccn4n3)C(F)(F)C2)cc1

InChI Key InChIKey=OUCYNWHQWAGIGA-UHFFFAOYSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435145   

TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Rugen Holdings (Cayman)

US Patent
LigandChemical structure of BindingDB Monomer ID 435145BDBM435145(US10584127, Compound E1-9.2 | US11136328, Compound...)
Affinity DataIC50: 1.00E+7nMAssay Description:This example describes an NR2B receptor binding assay in rat brain using [3H] (E)-N1-(2-methoxybenzyl)-cinnamidine (see below). The binding assay met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
US Patent