BDBM435445 US10570116, Compound C53

SMILES CC(C)(CC(=O)N1CCC(CC1)C(=O)c1cccc(c1)C(O)=O)Cc1cc2ccccc2c(=O)[nH]1

InChI Key InChIKey=QKUQIWILQMTNRG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435445   

TargetPoly [ADP-ribose] polymerase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM435445(US10570116, Compound C53)
Affinity DataIC50:  9.20E+3nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF® (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Merck Patent

US Patent
LigandPNGBDBM435445(US10570116, Compound C53)
Affinity DataIC50:  0.690nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Merck Patent

US Patent
LigandPNGBDBM435445(US10570116, Compound C53)
Affinity DataIC50:  1.10nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent