BDBM435484 US10570118, Example 38::US10570118, Example 39

SMILES COc1cc(cc2cc(CC3CN(C3)C(=O)C=C)n(-c3cccc(-c4cc(C(N)=O)n(C)c4)c3CO)c(=O)c12)C1CC1

InChI Key InChIKey=CVGVQKHYULEMCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 435484   

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM435484(US10570118, Example 39 | US10570118, Example 38)
Affinity DataIC50: 110nMAssay Description:A Lanthscreen Eu Kinase Binding assay (Life Technologies) was performed to quantitate the ability of test compounds to bind to BTK. The assay is base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM435484(US10570118, Example 39 | US10570118, Example 38)
Affinity DataIC50: 250nMAssay Description:A Lanthscreen Eu Kinase Binding assay (Life Technologies) was performed to quantitate the ability of test compounds to bind to BTK. The assay is base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent