BDBM435571 7-((2R,3R,4S,5R)-5-(((2-aminoquinolin-7- yl)oxy)methyl)-3,4-dihydroxy-4- methyltetrahydrofuran-2-yl)-3,7- dihydro-4H-pyrrolo[2,3-d]pyrimidin-4- one O-methyloxime::US10570140, Example 32

SMILES CO\N=C1/NC=NC2C1C=CN2[C@@H]1O[C@H](COc2ccc3ccc(N)nc3c2)[C@@](C)(O)[C@H]1O

InChI Key InChIKey=ZGEWUHKMLCRENE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435571   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM435571(US10570140, Example 32 | 7-((2R,3R,4S,5R)-5-(((2-a...)
Affinity DataIC50: 10nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent