BDBM435617 (2S,3S,4R,5R)-5-(4-amino-7H-pyrrolo[2,3- d]pyrimidin-7-yl)-N-(3- (aminomethyl)phenyl)-3,4-dihydroxy-3- methyltetrahydrofuran-2-carboxamide::US10570140, Example 43::US11078205, Example 43

SMILES C[C@]1(O)[C@@H](O)[C@@H](O[C@@H]1C(=O)Nc1cccc(CN)c1)n1ccc2c(N)ncnc12

InChI Key InChIKey=UDIXSGFSZTVKMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 435617   

TargetProtein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM435617(US10570140, Example 43 | (2S,3S,4R,5R)-5-(4-amino-...)
Affinity DataIC50: 825nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM435617(US10570140, Example 43 | (2S,3S,4R,5R)-5-(4-amino-...)
Affinity DataIC50: 825nMAssay Description:Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tris-HCl, pH 8.5,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent