BDBM435716 US10570141, Example 5

SMILES CS(=O)(=O)c1cc2cnc(Nc3ccc(cn3)C3CCNCC3)nc2n1C1CCCC1

InChI Key InChIKey=DHFGHSZKOLMKGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 435716   

TargetCyclin-dependent kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435716(US10570141, Example 5)
Affinity DataIC50: 1.46nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetCyclin-dependent kinase 6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM435716(US10570141, Example 5)
Affinity DataIC50: 9.85nMAssay Description:LANCE method of PerkinElmer Inc. was used in the assay, and recombinant CDK4/CyclinD3 (Item No.: 04-105) and CDK6/CyclinD3 (Item No.: 04-107) kinases...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent