BDBM435829 US10570167, Cpd. # 149::US11034715, Cpd. # 149

SMILES C[C@@]1(O)[C@@H](COC(Cc2ccccc2)(C(O)=O)C(O)=O)O[C@H]([C@@H]1O)n1cnc2c(N)nc(Cl)nc12

InChI Key InChIKey=SIFNQMMHUWWMKM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 435829   

Target5'-nucleotidase(Human)
Calithera Biosciences

Curated by ChEMBL
LigandPNGBDBM435829(US10570167, Cpd. # 149 | US11034715, Cpd. # 149)
Affinity DataIC50: 51nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
Target5'-nucleotidase(Human)
Calithera Biosciences

Curated by ChEMBL
LigandPNGBDBM435829(US10570167, Cpd. # 149 | US11034715, Cpd. # 149)
Affinity DataIC50: 51nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

Target5'-nucleotidase(Human)
Calithera Biosciences

Curated by ChEMBL
LigandPNGBDBM435829(US10570167, Cpd. # 149 | US11034715, Cpd. # 149)
Affinity DataIC50: 51nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2021
Entry Details
US Patent

Target5'-nucleotidase(Human)
Calithera Biosciences

Curated by ChEMBL
LigandPNGBDBM435829(US10570167, Cpd. # 149 | US11034715, Cpd. # 149)
Affinity DataIC50: 169nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed