BDBM435901 5-[3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methyl-phenyl]-1,3-dihydrobenzimidazol-2-one;::US10611730, Example 73

SMILES Cc1c(-c2ccc3[nH]c(=O)[nH]c3c2)cccc1-c1noc(C2CC2)n1

InChI Key InChIKey=FZQKXUOLMFIQEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435901   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 435901BDBM435901(US10611730, Example 73 | 5-[3-(5-Cyclopropyl-1,2,4...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent