BDBM436037 4-Chloro-3-(2-oxo-1,3-dihydrobenzimidazol-5-yl)-2-(trifluoromethoxy)benzonitrile;::US10611730, Example 209

SMILES N#Cc1ccc(Cl)c(-c2ccc3[nH]c(=O)[nH]c3c2)c1OC(F)(F)F

InChI Key InChIKey=YGLLJFHBVCSNBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436037   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436037BDBM436037(US10611730, Example 209 | 4-Chloro-3-(2-oxo-1,3-di...)
Affinity DataIC50: 15.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
US Patent