BDBM436042 6-(2-Chloro-6-(trifluoromethoxy)phenyl)-4-fluoro-1,3-dihydro-2H-::US10611730, Example 214

SMILES O=c1[nH]c2cc(-c3c(Cl)cccc3OC(F)(F)F)cc(F)c2[nH]1

InChI Key InChIKey=AVZJIOUPKUKNSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436042   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 436042BDBM436042(US10611730, Example 214 | 6-(2-Chloro-6-(trifluoro...)
Affinity DataIC50: 2.51nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent