BDBM436049 N-(2-(2-((2-Methoxy-4-(piperidin-4-yl)phenyl)amino)thieno[3,2-d]pyrimidin-7-yl)phenyl)-N-methylmethanesulfonamide ::US10611770, Compound 1

SMILES COc1cc(ccc1Nc1ncc2scc(-c3ccccc3N(C)S(C)(=O)=O)c2n1)C1CCNCC1

InChI Key InChIKey=DTRMTFJCMFBVBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436049   

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM436049(US10611770, Compound 1 | N-(2-(2-((2-Methoxy-4-(pi...)
Affinity DataIC50: 5.5nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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