BDBM436060 US10611777, Compound 9

SMILES C[C@@H](Nc1ncnc2[nH]cc(C#N)c12)c1cc2ncc(Cl)n2nc1-c1ccccc1

InChI Key InChIKey=ZNOQCQOSJQSWLD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 436060   

LigandPNGBDBM436060(US10611777, Compound 9)
Affinity DataIC50: 2nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent

LigandPNGBDBM436060(US10611777, Compound 9)
Affinity DataIC50: 46nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM436060(US10611777, Compound 9)
Affinity DataIC50: 158nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent