BDBM436065 8-(5-Fluoro-2-methoxyphenyl)-N-[4-(piperidin-4-yl)-2,3-dihydro-1-benzofuran-7-yl]quinazolin-2-amine ::US10611770, Compound 29

SMILES COc1ccc(F)cc1-c1cccc2cnc(Nc3ccc(C4CCNCC4)c4CCOc34)nc12

InChI Key InChIKey=OAKMMARRQBCUAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436065   

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM436065(US10611770, Compound 29 | 8-(5-Fluoro-2-methoxyphe...)
Affinity DataIC50: 14nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent