BDBM436067 4-[7-({8-[2-Methoxy-4-(trifluoromethyl)phenyl]quinazolin-2-yl}amino)-2,3-dihydro-1-benzofuran-4-yl]-piperidin-3-ol ::US10611770, Compound 31

SMILES COc1cc(ccc1-c1cccc2cnc(Nc3ccc(C4CCNCC4O)c4CCOc34)nc12)C(F)(F)F

InChI Key InChIKey=NWGXCHQOMDQXAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436067   

TargetALK tyrosine kinase receptor(Human)
Guangzhou Maxinovel Pharmaceuticals

US Patent
LigandPNGBDBM436067(US10611770, Compound 31 | 4-[7-({8-[2-Methoxy-4-(t...)
Affinity DataIC50: 2.30nMAssay Description:Buffer preparation: 50 mM HEPES, pH 7.5, 0.00015% Brij-35.The compound was configured as a concentration gradient in 100% DMSO and added to a 384-wel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent