BDBM436129 (chiral)-4-amino-6-((1-(3-chloro-6-(3-(2-hydroxypropan-2-yl)phenyl)imidazo[1,2-b]pyridazin-7-yl)ethyl)amino)pyrimidine-5-carbonitrile::US10611777, Compound 79

SMILES COc1ccc(CN(Cc2ccc(OC)cc2)c2cc([C@@H](C)N[S@](=O)C(C)(C)C)c(Cl)nn2)cc1

InChI Key InChIKey=JJOFQZSFNSGSRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436129   

LigandPNGBDBM436129(US10611777, Compound 79 | (chiral)-4-amino-6-((1-(...)
Affinity DataIC50: 2nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent