BDBM436132 (S)-N4-(1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl)-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyrimidine-4,6-diamine::US10611777, Compound 82

SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2nccn2nc1-c1ccccc1

InChI Key InChIKey=DTFBHUVVWSKYPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436132   

LigandPNGBDBM436132(US10611777, Compound 82 | (S)-N4-(1-(3-chloro-6-ph...)
Affinity DataIC50: 13nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent

LigandPNGBDBM436132(US10611777, Compound 82 | (S)-N4-(1-(3-chloro-6-ph...)
Affinity DataIC50: 203nMAssay Description:PI3K kinases including p110α/p85α and p110γ were purchased from Invitrogen, p110δ/p85α and p110β/p85α were from Mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent