BDBM436625 (S)-6-(2-fluoro-4-(3- (methylamino)-1- (thiophen-2- yl)propoxy)benzyl)-2- methoxy-9-methyl- 6,7,8,9-tetrahydro- 5H-pyrimido[4,5- e][1,4]diazepin-5-one::US10590140, Example 401

SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)c(F)c1)c1cccs1

InChI Key InChIKey=DELMUTDNAZXUCT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436625   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103](Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM436625(US10590140, Example 401 | (S)-6-(2-fluoro-4-(3- (m...)
Affinity DataKi: <100nMAssay Description:α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
US Patent