BDBM437181 US12534451, Compound PZ-4202

SMILES CS(=O)(=O)Nc1ccc(CC(=O)N2CCN(c3ccc(C#N)nn3)CC2)cc1

InChI Key InChIKey=LHSUDPHLKGVUSJ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437181   

TargetPantothenate kinase 3(Human)
St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 437181BDBM437181(US12534451, Compound PZ-4202)
Affinity DataIC50: 3.90nMAssay Description:PANK activity assay was performed in the presence of 0-10 μM compound in a reaction mixture that contained 100 mM Tris-HCl, pH 7.5, 10 mM MgCl2, 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)