BDBM437218 US12534451, Compound PZ-4352

SMILES O=C(Cc1ccc(C2CC2)cc1F)N1CCN(c2nc3ncc(F)cc3o2)CC1

InChI Key InChIKey=OUHGRNWLKXAVMD-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437218   

TargetPantothenate kinase 3(Human)
St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 437218BDBM437218(US12534451, Compound PZ-4352)
Affinity DataIC50: 0.860nMAssay Description:PANK activity assay was performed in the presence of 0-10 μM compound in a reaction mixture that contained 100 mM Tris-HCl, pH 7.5, 10 mM MgCl2, 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)