BDBM437274 4-(1-benzyl-1H-pyrazol-4-yl)-2-methylisoquinolin-1(2H)-one::US10617680, Example 8::US11020380, Example 8

SMILES Cn1cc(-c2cnn(Cc3ccccc3)c2)c2ccccc2c1=O

InChI Key InChIKey=CQDISTYJHAUKNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437274   

TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437274(4-(1-benzyl-1H-pyrazol-4-yl)-2-methylisoquinolin-1...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM437274(4-(1-benzyl-1H-pyrazol-4-yl)-2-methylisoquinolin-1...)
Affinity DataIC50: <500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent