BDBM437285 5-(1-(1-(2-chlorophenyl)ethyl)-1H-pyrazol-4-yl)-1- methylpyridin-2(1H)-one::US10617680, Example 19::US11020380, Example 19

SMILES CC(c1ccccc1Cl)n1cc(cn1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=ZTQADZPCKYDWQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437285   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437285(5-(1-(1-(2-chlorophenyl)ethyl)-1H-pyrazol-4-yl)-1-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437285(5-(1-(1-(2-chlorophenyl)ethyl)-1H-pyrazol-4-yl)-1-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent