BDBM437510 2-{4-[4-(2-Methoxy-pyrimidin-5-yl)-1-methyl-6-oxo-1,6- dihydro-pyridin-3-yl]-pyrazol-1-yl}-benzonitrile::US10617680, Example 244::US11020380, Example 244

SMILES COc1ncc(cn1)-c1cc(=O)n(C)cc1-c1cnn(c1)-c1ccccc1C#N

InChI Key InChIKey=JCMRDQYFQDXBBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437510   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437510(2-{4-[4-(2-Methoxy-pyrimidin-5-yl)-1-methyl-6-oxo-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437510(2-{4-[4-(2-Methoxy-pyrimidin-5-yl)-1-methyl-6-oxo-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent