BDBM437520 2-[4-(1,5-Dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)- pyrazol-1-yl]-benzonitrile::US10617680, Example 254::US11020380, Example 254

SMILES Cc1cc(cn(C)c1=O)-c1cnn(c1)-c1ccccc1C#N

InChI Key InChIKey=NJHAVBVIJWQSLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437520   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437520(2-[4-(1,5-Dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM437520(2-[4-(1,5-Dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent