BDBM437666 US10617692, Compound III

SMILES Nc1nn(cc1-c1ncnc2[nH]ccc12)C(CC#N)C1CCC(=O)C1

InChI Key InChIKey=CNCXBBAZLFRYTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437666   

TargetTyrosine-protein kinase JAK2(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM437666(US10617692, Compound III)
Affinity DataIC50: 10nMAssay Description:A testing platform for kinase activity of JAK2 was established based on Homogeneous Time-Resolved Fluorescence (HTRF) assay, and the activities of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent