BDBM437669 US10617706, Example 103

SMILES O=C1NC2N(c3ccc4OCOc4c3)c3cc(ccc3C=C2C(=O)N1)C#N

InChI Key InChIKey=NSHLXHVHWCOJJC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437669   

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM437669(US10617706, Example 103)
Affinity DataIC50: 964nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent