BDBM437675 US10617706, Example 109::US10617706, Example 110

SMILES OC(=O)c1cccc(Oc2ccc(cc2)N2C3NC(=O)NC(=O)C3=Cc3ccc(cc23)C#N)c1

InChI Key InChIKey=GEPBHWPMDIOEKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437675   

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM437675(US10617706, Example 110 | US10617706, Example 109)
Affinity DataIC50: 186nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Regents of The University of Minnesota

US Patent
LigandPNGBDBM437675(US10617706, Example 110 | US10617706, Example 109)
Affinity DataIC50: 934nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent