BDBM437727 2-(1H-Benzimidazol-2-yl)-6-(1-ethyl-1H-indazol-6-yl)-1,3-benzoxazole::US10596184, Example 31

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cc(cnc1F)-c1ccc2nc(oc2c1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=FZEPAALSJXFHAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437727   

LigandPNGBDBM437727(2-(1H-Benzimidazol-2-yl)-6-(1-ethyl-1H-indazol-6-y...)
Affinity DataIC50: 250nMAssay Description:PI3Kdelta: The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

LigandPNGBDBM437727(2-(1H-Benzimidazol-2-yl)-6-(1-ethyl-1H-indazol-6-y...)
Affinity DataIC50: 250nMAssay Description:PI3K-gamma:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent