BDBM437794 (2S)-3-(4- fluorophenyl)sulfonyl-N-[[6- [6-(trifluoromethyl)-3- pyridyl]pyrimidin-4- yl]methyl]-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 3

SMILES Fc1ccc(cc1)S(=O)(=O)N1C2CC(C2)[C@H]1C(=O)NCc1cc(ncn1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=YMFGGDYCPOYHOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437794   

LigandPNGBDBM437794((2S)-3-(4- fluorophenyl)sulfonyl-N-[[6- [6-(triflu...)
Affinity DataIC50: 24.8nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent