BDBM437847 (2S)-3-(4- fluorophenyl)sulfonyl-N-[[5- fluoro-4-[2- (trifluoromethyl)pyrimidin-5- yl]-2-pyridyl]methyl]-4- methyl-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 12

SMILES CC12CC(C1)[C@H](N2S(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc(c(F)cn1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=USAGPZWYANUJPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437847   

LigandPNGBDBM437847((2S)-3-(4- fluorophenyl)sulfonyl-N-[[5- fluoro-4-[...)
Affinity DataIC50: 90.2nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent