BDBM437881 (2S)-N-[[2-fluoro-5-[2-methyl- 5-(trifluoromethyl)pyrazol-3- yl]phenyl]methyl]-3-(4- fluorophenyl)sulfonyl-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 18

SMILES Cn1nc(cc1-c1ccc(F)c(CNC(=O)[C@@H]2C3CC(C3)N2S(=O)(=O)c2ccc(F)cc2)c1)C(F)(F)F

InChI Key InChIKey=AWJNHJJDIQNDBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437881   

LigandPNGBDBM437881((2S)-N-[[2-fluoro-5-[2-methyl- 5-(trifluoromethyl)...)
Affinity DataIC50: 15.7nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent