BDBM437886 (2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- fluoro-5-[6-(trifluoromethyl)- 3-pyridyl]phenyl]methyl]-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 20

SMILES Fc1ccc(cc1)S(=O)(=O)N1C2CC(C2)[C@H]1C(=O)NCc1cc(F)cc(c1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=PIQPHIMHFLBFPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437886   

LigandPNGBDBM437886((2S)-3-(4- fluorophenyl)sulfonyl-N-[[3- fluoro-5-[...)
Affinity DataIC50: 6.11nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent