BDBM437908 (2S)-N-[[5-(difluoromethyl)-2- [2-(trifluoromethyl)pyrimidin- 5-yl]-4-pyridyl]methyl]-3-(3,4- difluorophenyl)sulfonyl-3- azabicyclo[2.1.1]hexane-2- carboxamide::US10597383, Example 25

SMILES FC(F)c1cnc(cc1CNC(=O)[C@@H]1C2CC(C2)N1S(=O)(=O)c1ccc(F)c(F)c1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=XBQMHSMYPIFZEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437908   

LigandPNGBDBM437908((2S)-N-[[5-(difluoromethyl)-2- [2-(trifluoromethyl...)
Affinity DataIC50: 9.01nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent