BDBM437971 US10596172, Compound I-379::US11351168, Compound I-379

SMILES Fc1cnc(Nc2ccc(OCCOCCOCCN=[N+]=[N-])cc2)nc1Nc1cccc(NC(=O)C=C)c1

InChI Key InChIKey=YMXHAQIYPQGATN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 437971   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM437971(US10596172, Compound I-379 | US11351168, Compound ...)
Affinity DataIC50: <10nMAssay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM437971(US10596172, Compound I-379 | US11351168, Compound ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM437971(US10596172, Compound I-379 | US11351168, Compound ...)
Affinity DataIC50: <100nMAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM437971(US10596172, Compound I-379 | US11351168, Compound ...)
Affinity DataIC50:  550nMAssay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent