BDBM437980 US10597399, Compound S2

SMILES CC1CN(Cc2nnc(C3COC(C)(C)N3C(=O)OC(C)(C)C)n12)C(=O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

InChI Key InChIKey=JHTJTHLEEMIMBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437980   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM437980(US10597399, Compound S2)
Affinity DataIC50: 20nMAssay Description:The HTb-PARP-1 positive clones were obtained using the full-length PARP-1 plasmid, through PCR amplification, enzyme digestion, ligation, and transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent