BDBM438121 US10618886, Compound XIV

SMILES Cc1nc2ccc(cc2c(=O)n1-c1ccc(OC2CCC(CC2)C2CC2)cc1)S(F)(F)(F)(F)F

InChI Key InChIKey=LKTLNFLJDVNOCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438121   

TargetHistamine H3 receptor(Human)
Xw Laboratories

US Patent
LigandPNGBDBM438121(US10618886, Compound XIV)
Affinity DataIC50: 55.7nMAssay Description:Briefly, for membrane parathion, HEK293/Ga15/hH3R cells were grown to confluence, harvested and the cell pellets were suspended in TEL buffer (50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Xw Laboratories

US Patent
LigandPNGBDBM438121(US10618886, Compound XIV)
Affinity DataIC50: 61.9nMAssay Description:Briefly, for membrane parathion, HEK293/Ga15/hH3R cells were grown to confluence, harvested and the cell pellets were suspended in TEL buffer (50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent