BDBM438292 (+)-4-Chloro-5-fluoro-1-[2-oxo-2-[2-(2,2,2-trifluoroethyl)pyrrolidin-1-yl]ethyl]-1′-(1H-pyrazolo[4,3-b]pyridine-5-carbonyl)spiro[indole-3,4′-piperidine]-2-one::US10618897, Example 113

SMILES Fc1ccc2N(CC(=O)N3CCC[C@@H]3CC(F)(F)F)C(=O)C3(CCN(CC3)C(=O)c3ccc4[nH]ncc4n3)c2c1Cl

InChI Key InChIKey=MMMOLCFLTDJEJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438292   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438292((+)-4-Chloro-5-fluoro-1-[2-oxo-2-[2-(2,2,2-trifluo...)
Affinity DataIC50: 30.1nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent