BDBM438293 US10618897, Example 114::US10618897, Example 115

SMILES Fc1ccc2N(CC(=O)N3CCC4CCCC34)C(=O)C3(CCN(CC3)C(=O)c3ccc4[nH]ncc4n3)c2c1Cl

InChI Key InChIKey=FOZKCHYNGWWLBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 438293   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438293(US10618897, Example 115 | US10618897, Example 114)
Affinity DataIC50: 30.9nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM438293(US10618897, Example 115 | US10618897, Example 114)
Affinity DataIC50: 39.5nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent