BDBM438722 21-isopropyl-23-methyl-21H-6,11-dioxa-3-aza- 2(5,7)-pyrazolo[4,3-b]pyridina-1,5(3,2)- dipyridinacycloundecaphane::US10618913, Example 1

SMILES COc1ccc(CN2Cc3cccnc3OCCCCOc3ncccc3-c3cc2c2n(nc(C)c2n3)C(C)C)cc1

InChI Key InChIKey=YLWZUCCUGZMSMM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 438722   

LigandPNGBDBM438722(21-isopropyl-23-methyl-21H-6,11-dioxa-3-aza- 2(5,7...)
Affinity DataIC50:  12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM438722(21-isopropyl-23-methyl-21H-6,11-dioxa-3-aza- 2(5,7...)
Affinity DataIC50:  20nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM438722(21-isopropyl-23-methyl-21H-6,11-dioxa-3-aza- 2(5,7...)
Affinity DataIC50:  1.40nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent