BDBM439016 US10604502, Ex # 15::US10604502, Ex # 4

SMILES Cc1cc2n(cc(-c3cncc(N)c3C(F)F)c2cc1C#N)[C@@H]1CC[C@H](O)CC1

InChI Key InChIKey=QUJFBNMYCIPXMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439016   

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandPNGBDBM439016(US10604502, Ex # 15 | US10604502, Ex # 4)
Affinity DataIC50: 26nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandPNGBDBM439016(US10604502, Ex # 15 | US10604502, Ex # 4)
Affinity DataIC50: 27nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent