BDBM439036 3-(3-amino-2-methylphenyl)-1-(3-hydroxypropyl)-2,6-dimethyl-1H-indole-5-carbonitrile::US10604502, Ex # 24

SMILES Cc1c(-c2cccc(N)c2C)c2cc(C#N)c(C)cc2n1CCCO

InChI Key InChIKey=VANWIPMZSKAOOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 439036   

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandPNGBDBM439036(3-(3-amino-2-methylphenyl)-1-(3-hydroxypropyl)-2,6...)
Affinity DataIC50: 5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent