BDBM439055 3-(5-amino-4-chloropyridin-3-yl)-1-(1,1-dioxidothietan-3-yl)-6-methyl-1H-indole-5-carbonitrile::US10604502, Ex # 43

SMILES Cc1cc2n(cc(-c3cncc(N)c3Cl)c2cc1C#N)C1CS(=O)(=O)C1

InChI Key InChIKey=CZXOZUOXQOAZNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 439055   

TargetLysine-specific histone demethylase 1A(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 439055BDBM439055(3-(5-amino-4-chloropyridin-3-yl)-1-(1,1-dioxidothi...)
Affinity DataIC50: 588nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of twelve concentrations. The...More data for this Ligand-Target Pair
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Date in BDB:
12/20/2020
Entry Details
US Patent