BDBM439194 US10604514, Compound 70

SMILES CN1CCN(C[C@H]2CC[C@@H](CC2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnc(C)o2)CC1

InChI Key InChIKey=QZRRUZISVUJLOV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439194   

LigandPNGBDBM439194(US10604514, Compound 70)
Affinity DataEC50:  2nMAssay Description:Briefly, recombinant DYRK1A kinase, ATP and Ser/Thr peptide 18 were prepared in 1 Kinase buffer to final concentrations of 0.19 μg/mL, 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM439194(US10604514, Compound 70)
Affinity DataEC50:  73nMAssay Description:Briefly, recombinant GSK3β kinase, ATP and Ser/Thr peptide 09 are prepared in 1 Kinase buffer to final concentrations of 0.04 μg/mL, 46 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
US Patent