BDBM439247 (S)-4-(3-(but-2-ynamido)piperidin-1-yl)-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide::US10604504, Example 123

SMILES CC#CC(=O)NC1CCCN(C1)c1c(F)cc(C(N)=O)c2[nH]c(C)c(C)c12

InChI Key InChIKey=VJPPLCNBDLZIFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 439247   

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM439247((S)-4-(3-(but-2-ynamido)piperidin-1-yl)-5-fluoro-2...)
Affinity DataIC50: 0.0900nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent