BDBM439287 US10604514, Compound 225

SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)c3cc[n+]([O-])c(c3)N3CC[N+](C)([O-])CC3)cc2c1

InChI Key InChIKey=FHTLSGGKBWSYIF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439287   

LigandPNGBDBM439287(US10604514, Compound 225)
Affinity DataEC50:  2nMAssay Description:Briefly, recombinant DYRK1A kinase, ATP and Ser/Thr peptide 18 were prepared in 1 Kinase buffer to final concentrations of 0.19 μg/mL, 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM439287(US10604514, Compound 225)
Affinity DataEC50:  407nMAssay Description:Briefly, recombinant GSK3β kinase, ATP and Ser/Thr peptide 09 are prepared in 1 Kinase buffer to final concentrations of 0.04 μg/mL, 46 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
US Patent