BDBM440922 US10639284, Compound 3.091::US11426364, Compound 3.091

SMILES Cn1cnc(CNCc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3ccccc3F)cc2OCc2cncc(c2)C#N)c1

InChI Key InChIKey=ABNWHXQDLCZMDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 440922   

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM440922(US10639284, Compound 3.091 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4 ° C. The wells were then blocked with PBS containing 2% BSA i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2021
Entry Details
US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM440922(US10639284, Compound 3.091 | US11426364, Compound ...)
Affinity DataIC50: 100nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent