BDBM441021 1-[3-Methyl-4-(2-oxo-3-aza-bicyclo[3.1.0]hex-3-ylmethyl)-benzyl]-1H-pyrazole-4-carboxylic acid ((R)-2-amino-6,7-dihydro-5H-[1]pyrindin-5-yl)-amide::US10640486, Example 66

SMILES Cc1cc(Cn2cc(cn2)C(=O)N[C@@H]2CCc3nc(N)ccc23)ccc1CN1CC2CC2C1=O

InChI Key InChIKey=JVLHJWOGJFRGPB-PSGUAHCZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 441021   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM441021(1-[3-Methyl-4-(2-oxo-3-aza-bicyclo[3.1.0]hex-3-ylm...)
Affinity DataIC50:  18nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent